The new mutual objective attainment price both for BP and LDL-C was very low (22

Our multivariate logistic regression analysis showed that obesity, diabetes, coronary heart disease, cerebrovascular disease and chronic kidney disease were independent risk factors associated with BP target attainment failure. 9%) in our hypertensive dyslipidemia patients. For those with diabetes, CHD and/or CKD, the lower BP target (< mmHg) in the 2010 Chinese Hypertension Guideline may partially account for the disappointing BP attainment rates. However, the BP target rate in patients with obesity or cerebrovascular disease were also very low, though these patients shared the same BP target value (SBP/DBP < mmHg) as uncomplicated hypertensives. Moreover, the analysis of dyslipidemia management in DYSIS-China also revealed that diabetes was a strong predictor of failure in attaining LDL-C and non-HDL-C goals . Zhao's result are in accordance with the findings of our multivariate logistic regression analysis, which showed that diabetes was an independent risk factor for not achieving BP and combined BP and LDL-C targets. Therefore, besides the stricter BP target value for these comorbidities, there must be other reasons (vide supra) that may account for the low BP target attainment rates. Further measures should be taken to spread the recommendations of our guidelines in order to improve BP and LDL-C control rate in patients with comorbidities. The doctors in endocrine or neurology departments should focus more on the control of BP and LDL-C in their patients, though the circumstances in other departments were also not optimal in our study.

Regardless of if during the “Almost every other Divisions” the newest rates away from treated people (55.9% to own blood pressure and 62.4% to possess lipid minimizing pills) was not the highest (Extra document step one: Desk S1), the target attainment rates to possess BP (43.4%) (Additional file 2: Dining table S2), LDL-C (68%) (Desk 2) and you can one another BP and you can LDL-C (35.5%) (Additional file step three: Table S3) had been the best certainly all departments looked at. A possible explanation could be one to inside “Most other Divisions” the brand new frequency off comorbidities and you will exposure circumstances have been lower and you can a lot fewer people needed seriously to enjoys their BP and you may LDL-C around mmHg and dos.0 mmol/L, correspondingly

The present investigation has several constraints. Since it was an observational mix-sectional research, long-title effects couldn’t become examined. Concurrently, all the information of your patients’ compliance wasn’t gathered purposefully from inside the DYSIS-Asia. Hence we could perhaps not learn this new patients’ adherence to cures precisely in the modern study. Furthermore, all the people subscribed to DYSIS-Asia had currently obtained about 3 months antidyslipidemia medication (addition standards getting DYSIS-China) plus the therapy price away from statins within this diligent inhabitants is actually as high as 89.7%. When the DYSIS-Asia will have enrolled dyslipidemia victims consecutively and never removed clients versus earlier in the day antidyslipidemia procedures, the fresh statins’ cures rates might have yes started much lower than simply 89.7%, as well as the joint BP and you will LDL-C objectives attainment cost bad compared to those in the present study.


As the frequency of blood pressure level into the Chinese dyslipidemia patients was high, a significant ratio away from people don’t achieve the BP target, and each other BP and you will LDL-C goals. An incomplete administration program, incorrect monotherapy, poor diuretic medication and you will bad medication conformity could possibly get account fully for the discouraging objective attainment costs within the Chinese people with each other hypertension and you will dyslipidemia. The data from our research obviously advise that the brand new organization away from a sound management program for the treatment of blood pressure levels and dyslipidemia is always to be an essential healthcare method when you look at the China.


Wang Z, Chen Z, Zhang L, Wang X, Hao Grams, Zhang Z, Shao L, Tian Y, Dong Y, Zheng C, et al. Reputation regarding blood pressure levels for the Asia: comes from the fresh new China blood pressure level questionnaire, 2012-2015. Movement. 2018;–56.

Zhang M, Deng Q, Wang L, Huang Z, Zhou M, Li Y, Zhao Z, Zhang Y, Wang L. Incidence from dyslipidemia and you can achievement from lower-density lipoprotein cholesterol levels objectives within the Chinese grownups: a nationwide member survey out-of 163,641 people. Int J Cardiol. 2018;–203.

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